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Image Search Results
Journal: The Journal of veterinary medical science
Article Title: PEGylated lactoferrin enhances its hepatoprotective effects on acute liver injury induced by D-galactosamine and lipopolysaccharide in rats.
doi: 10.1292/jvms.09-0324
Figure Lengend Snippet: Fig. 3. Effect of PEGylated bLf on apoptosis in liver 8 hr after GalN/LPS injection in rats. Arrows indicate apop- totic cells. TUNEL staining. (a) animals treated with saline and GalN/LPS. (b) animals treated with native bLf and GalN/LPS. (c) animals treated with 20k-PEG-bLf and GalN/LPS. (d) animals treated with 40k-PEG-bLf and GalN/LPS. Bar=50 m.
Article Snippet: Apoptotic bodies were detected by terminal deoxynucleotidyltransferase (TdT)-mediated deoxyuridine triphosphatedigoxigenin (dUTP) nick-end labeling (TUNEL), which was performed using an in
Techniques: Injection, TUNEL Assay, Staining, Saline
Journal: PLoS ONE
Article Title: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
doi: 10.1371/journal.pone.0176599
Figure Lengend Snippet: ( A) Inhibition of GBM cell line proliferation following culture with CID613034 (black, 0 μM; blue, 0.5 μM; red, 1 μM; green, 2 μM) for the indicated time points. (*, P < 0.05). Data represent mean ±S.D. of three independent experiments. (B) CID613034 exposure inhibits anchorage-independent growth. Cells were suspended in soft agar to evaluate anchorage independent growth in the presence of the indicated concentrations of inhibitor and colonies counted after 14 days of growth. Data represent mean +S.D. of three independent experiments. (C) Migration of U87 and LN229 cells in the presence of the indicated concentration of CID613034. Cells were seeded into Boyden chambers and allowed to migrate towards BSA (white bars), vitronectin (grey bars) or fibronectin (black bars) (*, P <0.05). Data represent mean +S.D. of three independent experiments. (D) Invasive potential of U87 or LN229 cells in the presence of the indicated concentrations of CID613034 migrating through matrigel. Data represent mean +S.D. of three independent experiments. (E) Cell-cycle phase distributions were determined on the indicated lines treated with CID613034 as shown. One of three experiments with similar results is shown. (F) Percent apoptotic cells as determined via annexin V-FITC staining. Data represent mean +S.D. of three independent experiments.
Article Snippet: Cells were stained using a FITC-conjugated annexin V (
Techniques: Inhibition, Migration, Concentration Assay, Staining
Journal: PLoS ONE
Article Title: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
doi: 10.1371/journal.pone.0176599
Figure Lengend Snippet: Summary of anti-GBM effects of CID613034 analogs.
Article Snippet: Cells were stained using a FITC-conjugated annexin V (
Techniques: